What happens if I'm laid off after being nominated or while my PR is processing?

Tell the province promptly. Hiding a job loss can create misrepresentation problems far worse than the layoff itself. If your nomination was based on a job offer, the province may ask you to find a similar job in the province within a set time, or in some cases may withdraw the nomination. Many people do recover from a layoff by securing new in-province work quickly. Keep records of your job search and communicate honestly with both the province and IRCC.